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Cell Biology

By Dr. K. Sanatombi   |   Department of Biotechnology, Manipur University
Cell biology is an interdisciplinary subject integrating the fields of biochemistry, molecular cell biology and genetics. The aim of the course is to gives basic knowledge about the structure and function of cells and cellular components. The different modules of the course will examine different areas of cellular biology including structure and function of prokaryotic and eukaryotic cells, membrane and organelle structure and function, chemical composition of the cell, cell organelles and cellular communication. In this course, we will also examine the methods to fractionate cells and cellular components. The other important aspects of cell biology that will be discussed in the course includes: mechanisms behind organelle transport and secretion;; the structure and function of enzymes and kinetics of enzyme reactions; cell communication; intercellular contacts, cell surface receptors; extracellular matrices; signals over the plasma membrane, receptors, and cell signaling; the organisation and structure of the cell nucleus, chromatin and chromosomes.

Learners enrolled: 3361

SUMMARY

Course Status : Completed
Course Type : Core
Duration : 12 weeks
Start Date : 15 Jul 2019
End Date : 05 Oct 2019
Exam Date :
Category :
  • Biological Sciences & Bioengineering
  • Level : Undergraduate

    COURSE LAYOUT

    Week 1: Cells, Prokaryotic and Eukaryotic cells, Plant and animal cells, Chemical components of biological membranes
    Week 2: Organization and Fluid Mosaic Model, Extracellular Structures, Cytosol, Enzymes
    Week 3:   Eukaryotic Cell organelles, Mitochondria, Chloroplast, ribosomes and nucleus, Endoplasmic Reticulum, Golgi apparatus, Lysosomes and Peroxisomes, Membrane Vacuolar system
    Week 4: Cytoskeletons and Cell Membrane, Membrane Transport, Protein Trafficking, Ubiquitin Receptors and Protein Quality Control, Subcellular Fractionation
    Week 5: Nucleus: Structure and Function, Chromosomes and their structure Cell division: Comparison between Mitosis and Meiosis and crossing over, Symmetric and asymmetric cell divisions
    Week 6: Cell Cycle and its regulation, Regulation of DNA replication, Cell differentiation and stem cells, Tumor Suppressor Genes and Oncogenes
    Week 7:  Brief outline of Cancer Biochemistry and Cancer Phase of Cell Cycle, Cell Migration and Cancer Metastasis, Brief Treatment on cell culturing:         Apoptosis and ageing, Agents promoting  carcinogenesis
    Week 8: Autophagy, Nerve cell signaling, Signal Transduction by Cytokine and Nuclear Receptors, Signal Transduction by G proteins
    Week 9: Introduction to Lab Safety: Micro pipette use, solutions, dilutions, and unit conversions, Demonstration of dialysis, Study of plasmolysis and de-plasmolysis, Enzyme activity assay
    Week 10: Study of structure of Prokaryotic and Eukaryotic cell,Cell viability assay
     Study of mitosis in onion root, Preparation of Nuclear, Mitochondrial & cytoplasmic fractions
    Week 11:   Discussion/Interaction
    Week 12:  Discussion/Interaction

    BOOKS AND REFERENCES

    REFERENCES:
    Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, Keith; Walter, P., (eds) c2002: Molecular Biology of the Cell, Garland Science, New York and London.
    Copper, G.M., & Hausman, R.E., 2004: The Cell: A Molecular Approach, 3rd ed., Sinauer Associates, Inc, Sunderland, Massachusetts.
    Lodish, H. Berk A, Zipursky SL, et al., 2000: Molecular Cell Biology, 4th edition., W.H. Freeman, New York.

    LINKS:
    https://www.ncbi.nlm.nih.gov/books
    http://www.di.uq.edu.au/sparqglossary#b
    https://micro.magnet.fsu.edu
    https://cellbiology.med.unsw.edu.au

    INSTRUCTOR BIO



    Dr. K. Sanatombi is presently working as Assistant Professor in the Department of Biotechnology, Manipur University, since 2009. She holds more than nine years of post-graduate teaching experience in Biotechnology. Her main research interests are in the areas of Plant biotechnology, including in vitro secondary metabolite production and DNA profiling of medicinal and aromatic plants. She has published many research papers in international journals and contributed chapters in books published by international publishers.

    COURSE CERTIFICATE

    30% for in course Assessment & 70% of end-term Proctored Exam


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