Introduction to chemical evolution, Carbon fixation-Calvin cycle
to molecular interactions, types of bonds
Common bonding pattern for carbon, oxygen and nitrogen
Tutorial: VB theory
VB theory, hybridisation in methane, ammonia, amide, water, alkene, alkyne
MO theory, orbital overlap (s-s, s-p, p-p), bond order, s-p mixing
Electronic effects 1: Inductive effects and its significance
Electronic effects 2: Resonance effects and its significance
Electronic effects 3: Hyperconjugation and its significance
Tutorial: Acids and bases: Arrhenius, Brønsted-Lowry, and Lewis theories
Functional groups and their importance
Tutorial : Formal charge
Reactivity and intermediates
Carbocations, Carbanions, Free radicals and Carbenes
Types of organic reactions and their mechanism
Addition, Elimination, Substitution and radical reactions
Stereochemistry 1: Fischer, Newmann and Sawhorse Projections
Stereochemistry 2: Geometrical isomerism – cis/trans, E/Z notation, CIP rule
Optical Isomerism -enantiomer, diastereomer
Tutorial: Geometrical isomerism
Tutorial: enantiomer, diastereomer
Chemistry of alkanes: formation, Wurtz Reaction, Wurtz-Fittig Reactions, Reactions of alkanes
Markownikoff and Anti Markownikoff addition
Reactions of alkenes 1: Oxymercuration-demercuration, Hydroboration-oxidation, Ozonolysis
Tutorial: Electrophilic additions
Reactions of alkenes 2: Catalytic reduction, 1,2-and 1,4-addition, Diels-Alder reaction
Reactions of alkenes 3: Di-hydroxylation, Allylic and benzylic bromination and mechanism
Reactions of alkynes
Conformation of cycloalkanes 1
Conformation of cycloalkanes 2
Conformation of cyclohexane
Aromaticity 1: Huckel’s rule, aromatic character of cyclic C3 and C4 systems
Aromaticity 2: aromatic character of cyclic C5-C7 systems, heterocycles
Aromatic Electrophilic substitutions 1: Halogenation
Aromatic Electrophilic substitutions 2: Hammick and Illingworth empirical rule, Orientation
Aromatic Electrophilic substitutions 3: Nitration, sulphonation, Friedel-Crafts alkylations and acylation
March's Advanced Organic Chemistry Reactions, Mechanisms and Structure 5th Ed. Michael B. Smith, Jerry March, John Wiley & Sons, Inc., 2001.
F. A. Carey: Organic Chemistry, 5th Ed., McGraw-Hill, 2004.
Peter Sykes, A Guidebook to Mechanism in Organic Chemistry, 6th Ed, John Wiley and Sons. Inc, New York, 1986.
J. Clayden, N. Greeves, S. Warren, Organic Chemistry, 2nd Ed., Oxford University Press, New Delhi, 2012.
F. A. Carey and R. J. Sundberg, Advanced Organic Chemistry, Part A & B, 5th Ed., Springer, New York, 2007.
Paula Yurkanis Bruice, Organic Chemistry, 4th Ed. Prentice Hall, 2003.
D. Nasipuri, Stereochemistry of organic compounds, Principles and Applications, 3rd Ed. New Age International Publishers, 2018.
P. S. Kalsi, Stereochemistry: Conformation and Mechanism, 9th Ed, New Age International (P) Ltd., 2017.
Ernest L. Eliel, Samuel H. Wilen, Stereochemistry of Organic Compounds, Wiley India Ed, 2008.
I. L. Finar, Organic Chemistry, Volume 2: Stereochemistry and The Chemistry of Natural Products, Chapter 2, 5th Ed, Pearson Education India, 1956 Those who would like learn more about organic chemistry at a PG level can register for the course at Organic chemistry 1 Following are the other courses developed by Dr. Balaji which are available online for organic chemistry students with the support from SWAYAM Prabha TV Channel (CH15), IIT-M. Pharmaceutical Organic Chemistry III Organic Chemistry - III
“30 Marks will be allocated for Internal Assessment and 70 Marks will be allocated for external proctored examination”
There will be weekly graded evaluation. To get a certificate, you have to attempt weekly graded crossword puzzle 30% weight (best 5 out of 15 graded puzzle) and final proctored examination 70% weight. A 40 % pass individually (weekly assessment and proctored examination) is required to receive the certificate.
Best of 5 out of 15 graded quizzes/crossword puzzles will be considered for internal evaluation. The selection of 5 best quizzes will be spread over the entire 15 weeks. We will select 2 best quizzes from Week 1 to 5, another two from Week 6-10 and last one from Week 11-15.