The course on “Human Genetics” is a Discipline Specific Elective Course in Anthropology at undergraduate (UG) level under the Choice Based Credit System (CBCS). This is an introductory course designed primarily for students in the undergraduate or master’s programs interested in biomedical research, genetic counselling, medicine, and clinical genetics. This course is expected introduce the rapid advancements in our understanding the role of human genome in health and disease. The course is specially designed to supplement and enhance the understanding of students about different dimensions of human genetics starting from genes to proteins and mutations in genes to the genes in the evolution of humans. Furthermore, the course is focussed on history of human genetics, evolutionary genetics; Molecular evolution; DNA sequence variation and human origins. We would introduce key concepts of inheritance of human traits, pedigree analysis, and chromosome organization. Molecular biology tools used for understanding the genome, gene structure and gene mutations, gene mapping and gene cloning strategies will also be covered in this course. Objectives and outcome of human genome project, 1000 Genomes project and the HapMap project will also be discussed. The objectives of this course is to give the target audience/students an understanding of: Structure, Function and Inheritance of the human genome, the DNA structure and its replication, Recombination and DNA repair Mechanisms and Expression of genetic Information. The relationship between genes and protein, Transcription and RNA processing, Decoding the codons: the role of transfer RNAs, Genomic Variation, Genotype-phenotype correlations, Pedigree analysis and Expressivity, Chromosomal Basis of Genetic Disorders and Genetic mapping. The course will also focus on Concept of non-mendelian inheritance and complex diseases, Genomic Diversity & Human Evolution
| Course Status : | Upcoming |
| Course Type : | Elective |
| Language for course content : | English |
| Duration : | 12 weeks |
| Category : |
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| Credit Points : | 4 |
| Level : | Undergraduate |
| Start Date : | 05 Jan 2026 |
| End Date : | 30 Apr 2026 |
| Enrollment Ends : | 28 Feb 2026 |
| Exam Date : | 21 Jun 2026 IST |
| Translation Languages : | English |
| NCrF Level : | 5.0 |
| Exam shift : | II |
Note: This exam date is subject to change based on seat availability. You can check final exam date on your hall ticket.
Week-1
History of Human Genetics
Introduction to Hereditary and Inheritance
Human Genome
Structure of DNA
Week-2
Replication of DNA
DNA repair and recombination
Gene expression
Coding and Non-coding regions of DNA
Week-3
Basics of expression of Genetic information
Transcription
Translation
Post translational modifications
Week-4
Relationship between genes and protein
RNA processing
Genetic Code
Decoding the codons: encoding genetic information
Week-5
Transfer RNAs (tRNA) and its role
Introduction to Genomic Variation
Origins of Genetic Diversity
Genomic Polymorphisms
Week-6
SNPs, VNTR, CNVs, and Human Genetics
Haplotypes and haplogroups
Genotype-phenotype correlations
Introduction to Epigenetics
Week-7
Common mechanisms of Epigenetics
Epigenetics and diseases
Non-coding RNAs, micro-RNAs(miRNAs) & long noncoding RNAs (lncRNAs)
Introduction to Genetic Study in Humans
Week-8
Pedigree Analysis and Expressivity
Chromosomal Basis of Genetic Disorders
Karyotypes and identification of chromosome variation
Nucleic Acid Hybridization Assays
Week-9
Cytogenetic mapping
Genetic mapping (Microsatellite and other DNA polymorphisms)
LOD score
Sequencing strategies (PCR based Sanger sequencing to Exome sequencing)
Week-10
Concept of non-mendelian inheritance and complex diseases
Introduction to Genomic Diversity & Human Evolution
Human Evolution: An Overview
Evidence from mtDNA
Week-11
Evidences from Y-chromosome
Evolutionary genetics
DNA sequence variation and human origins
Biological and cultural evolution of humans
Week-12
Genetic Counselling
Assignment’s compilation
Examination
1. Human Molecular Genetics by Tom Strachan, Andrew P. Read Garland Science/Taylor & Francis Group, 2011
2. Essentials Of Human Genetics Fifth Edition (University Press)
By Manu L. Kothari, Lopa A. Mehta · 2009
3. Human Genetics: Concepts and Applications by Ricki Lewis
McGraw Hill Publishers 2020.
4. Human Genetics, 6th Edition, SD Gangane, Elsevier Publishers 2021
5. Principles of Genetics by EJ Gardner, MA, Simmons and DP Snustad, 8th Edition, Willey Press 2006.
TEACHING ASSISTANT
Ms. Sania Shams
Department of Bioresources
University of Kashmir
Dr. Manzoor Ahmad Mir holds Master’s Degree in Life Science with gold medal, qualified CSIR-JRF-NET three times; completed his Ph. D from Jawaharlal Nehru University New Delhi. Dr Manzoor has published more than 80 high-impact research papers with a cumulative impact factor of more than 520, i-10 index of 106, h-index of 34 with more than 3900 citations in just last five years. He has published 22 books and 85 book chapters with international publishers like Elsevier USA, Taylor & Francis and Springer-Nature. Dr. Manzoor has successfully guided 10 Ph. D scholars and 52 Masters Project Thesis. He has developed four MOOC courses in Immunology, Endocrinology, Human Genetics and Human Population Genetics for SWAYAM-UGC Ministry of Education, Govt of India. He is member of many scientific organizations like American Association of Cancer Research (AACR), American Oncology Association, American Society of Clinical Oncology (ASCO), European Society of Medical Oncology (ESMO), Fellow of Royal British Society (FRBS), International Immunology Association (IIA), Indian Cancer Society (ICS), Indian Immunology Society (IIS), Indian Immuno-oncology Society (IIoS), and many more. He is on the editorial board and Reviewer of many prestigious journals and have completed many guests edited collections for Scientific Reports by Nature Springer and Frontiers in Immunology. Dr Manzoor was awarded Teachers Associate Research Excellence Award by DST Govt of India in 2019 and Summer Research Fellowship by Indian Academy of Sciences and National Science Academy in 2020 and was awarded Best Researcher for his Breast Cancer Research and Awareness at Kashmir-Expo-2022 by DBT Govt of India and JKST&IC DST Govt of J&K. He has successfully organised many national and international conferences and DST-INSPIRE Science Camp for students. Dr Manzoor has visited more than 10 countries for his scientific presentations like USA, China, UK, Spain, UAE etc. He was the first nodal officer and coordinator of Kupwara University Campus and is the coordinator of IIS-Gujrat University Collaboration. Presently he is associate Professor & Head Department of Bioresources, University of Kashmir and Adjunct Professor, Indian Institute of sustainability (IIS)-Gujrat University Ahmadabad. Dr Manzoor has completed 5 research projects and currently has two on-going research projects. Dr Manzoor has figured in the top 2% Global Scientists list for the year 2023, 2024 and 2025 published by prestigious Stanford University USA in Health Sciences category.
1. End-Term Examination:
Weightage: 70% of the final result
Minimum Passing Criteria: 40%
2. Internal Assessment:
Weightage: 30% of the final result
Minimum Passing Criteria: 40%
Calculation of IA Marks:
Out of all graded weekly Assessments/Assignments, the top 50% of Assignments shall be considered for the calculation of the final Internal Assessment marks.
All students who obtain 40% marks in the internal Assessment and 40% marks in the end-term proctored exam separately will be eligible for the SWAYAM Credit Certificate.
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